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In a fixeddose study comparing placebo and 20, 40, and 60 mg of Paxil in the treatment non of OCD, there was no clear relationship between adverse events and the dose of Paxil to which patients were assigned. Visit the FDA MedWatch website prescription or call 1-800-FDA-1088. Suicidal thoughts prescription or actions: paxil and other antidepressant prescription medicines may increase suicidal thoughts or actions in some children, teenagers, or young adults within the first few months of treatment or when the dose is changed. Important: Use safety closures when dispensing this product unless otherwise directed by physician or requested by purchaser. The following table paxil provides the outcome classification by treatment group on Global Improvement items of the Clinical Global Impression (CGI) scale paxil for Study. There may be circumstances when it is necessary to initiate treatment with an maoi such as linezolid or intravenous methylene blue in a patient taking paxil. If anticholinergic effects are seen, the dose of procyclidine should be reduced. What is the most important information I should know about Paxil? The maximum dosage should not exceed 60 mg/day. In these studies, the effectiveness of Paxil compared to placebo was evaluated on the basis prescription of (1) the proportion of responders, as defined by a Clinical Global Impression (CGI) Improvement score of 1 (very much improved) or 2 (much. Prescribers or other health professionals should inform patients, their families, and their caregivers about the benefits and risks associated with treatment with Paxil and should counsel them in its appropriate use. The long-term maintenance effects of paxil in OCD were demonstrated in a long-term extension to Study. Table 2: Treatment-Emergent Adverse Experience Incidence in Placebo-Controlled Clinical Trials for Major Depressive Disordera Body System Preferred Term paxil (n 421) Placebo (n 421) Body as a Whole Headache 18 17 Asthenia prescription 15 6 Cardiovascular Palpitation 3 1 Vasodilation. The majority of patients in these trials were women (68 women: 377 out of 551 subjects in Study 1 and 66 paxil women: 202 non prescription out of 303 non subjects in Study 2). In a longer-term trial, paxil 566 patients meeting DSM-IV criteria for Generalized Anxiety Disorder, non who had responded during a single-blind, 8-week acute treatment phase with 20 to 50 mg/day of Paxil, were randomized to continuation of Paxil at their. Goddard C, Paton paxil C "Hyponatraemia associated with paroxetine." BMJ 305 (1992 1332. Musculoskeletal System: Frequent: Arthralgia ; infrequent: Arthritis, arthrosis ; rare: Bursitis, myositis, osteoporosis, generalized spasm, tenosynovitis, tetany. Some patients not responding to a 20-mg dose may benefit from dose increases, in 10-mg/day increments, up to a maximum of 50 mg/day. Impairment of Fertility: Some clinical studies have shown that ssris (including paroxetine) may affect sperm quality during ssri treatment, which may affect fertility in some men. Other Events Observed During The Premarketing Evaluation Of paxil During its premarketing assessment in major depressive disorder, multiple doses of paxil were administered to 6,145 paxil patients in phase 2 and 3 studies. Therefore, coadministration of Paxil with other drugs that are metabolized by this isozyme, including certain drugs effective in the treatment of major depressive disorder (e.g., nortriptyline, amitriptyline, imipramine, desipramine, and fluoxetine phenothiazines, risperidone, and Type 1C antiarrhythmics (e.g., propafenone, flecainide. Pregnancy Pregnancy Category.
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